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Saturday, 22 March 2014

Latest surgical camera that makes the smallest tumors seen with luminous dye

It can be difficult to see where a tumor begins and healthy tissue begins during surgery . But the new cameras can make operations detect and remove the cancer more successful .German researchers have developed a camera that makes cancer cells glow in bright colors . They say it will help surgeons distinguish between cancerous and healthy tissue when removing a tumor during surgery . It may even make it easier for the surgeon to remove the tumor completely - rather than leaving a small , hard - to- view cells .
A camera that detects tumors
Photo: Fraunhofer IPAThe camera makes the remnants of the tumor or metastasis of a millimeter in size , and that a surgeon might otherwise ignore , identified in detail ,
Before the surgery , doctors inject dye into the patient's blood . Fluorescent dyes are molecules that carry antibodies that are designed to attach to tumor cells . They are currently being tested in clinical studies .The molecules fluoresce blue , green , red or any other color - depending on the dye .To see color , and whether they have been attached to the tumor cells , tissue illuminate surgeon , during surgery , with the set of light at specific wavelengths .Camera superposes the normal color image with images showing each area glows with a fluorescent dye . Operators receive significantly more accurate information ,  And the patients operated under fluorescent lights have improved the chances of survival . Left : blue and green signs on the network
Left : The camera shows the network marked with a fluorescent dye . Right : Looking network without new camera

Left: blue and green marking on tissue. Right: no markings
Photo: Fraunhofer IPA
The camera can detect up to four dyes at a time .Injecting not just one but several dye into the patient's blood and see how it reacts to the tumor may also be helpful to know more about the biochemical structure of the tumor , the scientists said Nicholas Dimitriadis , who has worked on the camera .Detecting brain tumors" Seeing where the tumor ends and the healthy tissue begins very important with malignant brain tumors , " said Dimitriadis .When operating a brain tumor , the surgeon will aim to remove as little healthy tissue as possible, Dimitriadis said .But if one of the brain tumors ignored - even the tiniest bit - can become more aggressive and more deadly than the original tumor .To help with brain tumor surgery , the camera can detect the red dye has been used in tumor surgery .Doctors inject levulinic acid 5 - Amino ( 5 - ALA ) to the patient .Produce compounds in patients producing red dye in their cells . As tumors have increased metabolism , they accumulate higher amounts of this dye from other cells and can be " unmasked . "Presentation of the prototype in two weeksThis camera is available for testing in the operation . The researchers will present a prototype at Medica Trade Fair in Düsseldorf from November 20 to 23 .It is expected that the camera will be integrated into the surgical microscope or endoscope ." We plan to conduct our first clinical trial in 2014, " Dimitriadis said , " to figure out how to fit it to the clinic . "The trial will begin with a focus on brain tumor surgery .

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